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You say: "In the worst care scenario, a man with optimal treatment, a man that’s 80 years old may prefer to risk undergoing less aggressive therapy, because their risk of dying of other causes." But look at the vast improvement of irradiation, in just ~5 years, and look at the introduction of PSMA-PET just 4 years ago. With the advent of AI perhaps that risk might pay off with improvements in technology and knowledge? Care to comment on that?

Love your videos! A question: A short video on Agent Orange related PCa would be helpful to many. The Prostate Cancer Foundation states: "Men who were exposed to Agent Orange and other battlefield chemicals often present with more aggressive prostate cancer."

I am not quite sure I have the luxury of time. My PSA doubling time was 3 months then 6 weeks. Right now the cancer is self contained as far as we know. I am going for a PSMA PET scan in 2 weeks to confirm. To me, all the side effects are VERY concerning and I am looking at quality of life as a first desired outcome. My mom passed from cancer at 59. I just turned 59. Yeah, I guess I am a bit anxious.

I was diagnosed with Gleason 4+3 last week and already had 2 calls with your team. Absolutely nothing but GREAT things to say about them I was able to have much better conversations already with my doc. And I do have a great doc. He called me on a Sunday morning and spent 30 mins going over each question I had.

Not terribly helpful or informative. I would like to know my radiation exposure from PT PET/CT GA68 PSMA SKULL-THIGH. Then let me decide whether I consider the risk worth the benefit. It's condescending to treat us like children.

I can't say enough how important PCRI is to the entire prostate cancer patient community. I was like everyone who just assumed your doc had your best interest and would guide you to the 'best' treatment. When I was diagnosed a few years back with a T2 G3+4, my doc was all about surgery, yet I never mentioned I was watching these PCRI videos educating myself on all aspects of this. It was a video they posted last year with Dr. Kurtzman that changed my life. I ended up doing LDR brachytherapy with him due to watching that video and now 6 months out, my PSA is approaching .3 and have literally no side effects. I did at first, but it feels like I'm 'almost' 100% back to normal. Thanks Dr. Scholz for doing this.

Why no discussion of Dutasteride? Most clinical studies I have seen says it is superior to Finasteride, the same class of drug.

can u have .4 PSA with bone metz

I just finished my Harmon treatment and it was a problem I don't wish it on everyone but it helped me . Still have some side effects bone density and loss.

Titles are welcome for better understanding

Joel is a very hard working and intelligent person. He is educating his doctors. The doctors only know what was taught in medical school and follow approved protocols. They know the approved procedures to remove a prostate.

Since you all think this is the best authority on the Web Alex and Dr Scholz , please contribute a nice donation. I did but I didn't make it monthly I don't think. I will next month. I'm armed to the teeth to battle this

Thanks for posting . Very informative

such a inspiration!🤩

A lot of information in this show. Even though I didn't get to watch all the segments in their entirety, I plan to this re-watch this week. I want to thank PCRI for presenting this, and thank the presenters. I especially enjoy Drs. Scholz and Moyad and their discussions. The segment on addiction was very informative.

Radiation! Start with Brachytherapy then external beam! Radical surgery is not recommended. Way too radical with so many urinary side effects!

You never talk about just removing the cancer.

Don’t recommend hormone therapy. It’s chemical castraston.

I'm 77 years old and was diagnosed with Gleason 6 PCa about four years ago and have been on active surveillance . About a year and a half ago I started on Dutasteride and Tamsulosin and have been very pleased with the results. PSA numbers went down a bit , prostate size went down and I can sleep through the night. The only downside is a reduction in semen volume. However, there is one possible effect that appears to be very unusual and possibly incorrect. I just had an MRI (3T at a research university) and the two lesions that had been previously identified (MRI and biopsy) as Gleason 6 appear to have disappeared! I've asked them to re-check the MRI (but they are quite proud of their abilities) and plan to have a follow-up biopsy in August. Has anyone seen a similar result?

Great informative video as always. My doctor prescribed Dutasteride three years ago for BPH and prostatitis. It has been very effective in shrinking my prostate and lowering PSA. I am still taking it and the side effects have been minimal. I am wondering why my doctor prescribed Dutasteride instead of Finasteride and how they differ?

Another excellent presentation. Kudos to both of you. Great questions, wise answers.Thank you both.

Diagnosed? 1 22 2006. Date now? 6 30 2024. Still going strong. Reason? Wild Turkey 101.

Thank you all so much for the information. I can understand better about my husband's condition!

Thank you Dr for all you do for people

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Studies show that after 18 months or more of ADT CASTRATION, 75 percent of ALL MEN WILL NOT RECOVER THEIR TESTOSTERONE LEVELS EVEN AFTER A MEDIAN TIME OF FIVE YEARS. Please have the integrity to inform patients about the very long and unpredictable recovery time after ADT. This information is essential before patients can give FREE AND FULLY INFORMED CONSENT.

Help! G9 LN MET. Had radiation and 2 years ADT and zytiga. STAMPEDE seems to suggest 3 years ADT. MO insist 2 years enough. Thoughts?

Prostate cancer can be a silent killer for men even in their 40’s if not detected early by regular annual PSA blood tests. All men over 40 should be tested for PSA . Many cancers begin in prostate for men unfortunately . Many Dr’s do not place credence on PSA tests which is a trigger for biopsy of prostate cancer. Patients must demand biopsy if PSA is over 6 just to be on the safe side.

Thanks for posting.

Dr. MARK Scholz and Miss.Alex thank so much for this chemotherapy discussion because later on I need to decide whether need to go for chemotherapy after my Pet Scan report is being verified.I am having prostrate cancer too.

I just completed my six-month review following diagnosis of stage 4 PC in December 2023. At that time, my PSA was 86 and I had numerous lesions in my prostate, lymph nodes and multiple bones. I had triple therapy consisting of docetaxel (Taxotere), degarelix (Firmagon) and darolutamide (Nubeqa). I completed 5/6 cycles of docetaxel before the side effects became too great. These included loss of hair, energy, taste and appetite, diarrhoea, neuropathy, and bleeding under fingernails. I also needed several blood transfusions for low haemoglobin count. Side effects are slowly diminishing. After six months my PSA has fallen to 0.02, swelling in my prostate and lymph nodes has reduced, and I have no new cancer sites. No further chemo is planned for now, I will continue with degarelix and darolutamide for the foreseeable future. I had thought that the chemo would kill off the existing cancer in the bones, but that has not happened. My oncologist says that it not atypical. At least the cancer in the bones is not growing or spreading. Any thoughts on this? I am overall happy with the report. I no longer feel that I am in imminent danger.

Imua!!

Buenas tardes doctor, tengo 61 años y en una biopsia tengo los puntos de muestra 8, 9 y 10 con un Gleison 3+4=7, con 20%, 50% y 20% de incidencia... con dolor lumbar... ¿Qué recomiendas como tratamiento? Gracias

How many months must you be on Lupron before you can take a vacation? I had a two year vacation 7 lymph node metastasis throughout. Went back on Lupron psa immediately undetectable and lesions shrunk. Can I go right back to intermittent therapy?

If you're a hammer, everything looks like a nail...........If you're a surgeon, everything..........

I sm 4 months into adt with a starting psa of 121 rising to 230 while I waited for an appointment w ith a urologist. My psa has dropped but rate of dropping is decreasing. My mental health has never been worse. I cannot find a reason to live. I feel that the best outcome available will leave me in a level of misery where i will wish evrn harder to die. What to do?

what a tie! Mark's got style.

Pluvicto stopped after second treatment PSA doubled after first and shot up to over 2000 after 2nd. They talked about lower dose or adding more time til next treatment but blood tests before 3rd treatment weren’t great for hemoglobin, white cells, etc. Just had first treatment of Cabazitaxel and doctor said this is the last card up his sleeve. Anything left in your opinion?

I , age 62, had Leuprolide & 6 cycles of Docetaxel. After the 5th cycle my PSA dropped from 291 ng to 1.38 ng , ALP dropped from 1,195 U to 138 U. My Gleason score is 10 with bones mets. The doctor will add Abiraterone after chemos. How long can I live ?

Any advice for a 53 year old Prostate Cancer patient dealing with Autoimmune disorders (rheumatoid arthritis)? Gleason 9 treatment (radical prostatectomy, non-nerve sparing, radiation, Docetaxel, Lupron). Have had undetectable PSA for two years. Oncologist will not agree to let Rheumatologist prescribe methotrexate injection to alleviate symptoms. Currently surviving on prednisone and would like to stop steroids. There is little to no information to help guide decision making.

Got my biopsy done on Wednesday and will get the results on July 2nd. My PSA has come down to 3.3 in the last few weeks. I'm hoping what was seen on MRI was just a calcification. Anyone who is a believer, please pray for me.

I don't find anything said about a loss of orgasms in the days following low dose brachytherapy. Will it come back, and what are the stats about this point( without erectile disfunction)?

I must have a case for medical malpractice or even negligence since none of what he said about early detection being extremely rare prevented my bone metastasis. Anyone out there know a good attorney for me to contact about this ?

I had a TURP done in May for an enlarged prostate. The pathology came back with 6 of 133 samples indicating 4+4=8 Gleason score. My PSA went down after surgery, and I'm peeing like a 25 year old (I'm 67 years old). My next step is a MRI in one week. I'm very anxious. By the way, I feel Great! Thanks for your videos!

Grateful for Dr Sholz and for this fine young lady host they are really educating me to the point people are being referred for me for advise on prostate cancer and i am a chiropractor

My husband had Dr. Ankit Agarwal perform his LDR brachytherapy in the Phoenix area. He tremendously helped us, along with our local oncologist, urologist come up with the best treatment for my husband's prostate cancer. Dr. Agarwal is an amazing doctor, very highly rated and skilled specialist. He is very compassionate, and easy to talk to. He even called my husband a couple of times after the procedure, to check up on him. We are grateful to have found him.

Is ist possible to get a BPH after radiation ? And which treatments are than available?

My PSA is 16. MRI showed a lesion. Targeted biopsy showed 3 samples of stage one cancer. A PET scan was done. Gleason is 3+3. Now I'm getting 39 weeks of photon radiation and lupron. Does that sound right?

once you understand how anti-tumor immunity works, mainstreams "hormone therapy" makes no sense at all ....

Just wondering why they can't avoid the neurovascular bundles and internal arteries or using less radiation on those.